Clinical Case Studies: Employing Patient-specific Approaches to Care

(Presented twice. Register for the date that works best for you!)

Tuesday, July 16, 2019
3:00 p.m. – 4:00 p.m. ET

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Tuesday, July 23, 2019
12:00 p.m. – 1:00 p.m. ET

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Handout available at least 24 hours before webinar.

With the emergence of long-acting factors for the management and control of hemophilia A, it has become apparent that standardized dosing may not be appropriate. This educational activity will illustrate best practices in the prophylaxis and management of hemophilia A using patient cases. Various pharmacologic approaches for long-term prophylaxis and managing bleeds will be demonstrated, taking into account patient specific factors to be considered when selecting long-acting factors and treatment intervals, pharmacokinetics and target troughs, phenotype, and convenience.

Learning Objectives

  • Taking into account individual patient circumstances, determine the appropriate dose and interval of a long-acting factor.
  • Review the benefits of long-acting replacement products with respect to reduced frequency of administration, potential to achieve high trough levels, and the potential for improved adherence.
  • Illustrate situations (e.g., development of inhibitors, acute bleeds, development of a chronic illness, such as cardiovascular disease) that would require a change in therapy.


Sheh-Li Chen, Pharm.D., BCOP, CPP
Benign Hematology Clinical Pharmacist Practitioner
University of North Carolina Medical Center
Assistant Professor of Clinical Education
University of North Carolina Eshelmann School of Pharmacy
Chapel Hill, North Carolina

Target Audience

This activity was planned to meet the educational needs of pharmacists who care for patients with hemophilia.


This activity features slide presentations, active learning, and questions/discussion with faculty. 

CPE Information

ACPE #: 0204-000-19-408-L01-P
Activity Type: Application-based
CE Credits: 1.0 hour
Activity Fee: Free of charge

The American Society of Health-System Pharmacists is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.

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