Clinical Case Studies: Employing Patient-specific Approaches to Care

With the emergence of long-acting factors for the management and control of hemophilia A, it has become apparent that standardized dosing may not be appropriate. This educational activity will illustrate best practices in the prophylaxis and management of hemophilia A using patient cases. Various pharmacologic approaches for long-term prophylaxis and managing bleeds will be demonstrated, taking into account patient specific factors to be considered when selecting long-acting factors and treatment intervals, pharmacokinetics and target troughs, phenotype, and convenience.

Learning Objectives

  • Taking into account individual patient circumstances, determine the appropriate dose and interval of a long-acting factor.
  • Review the benefits of long-acting replacement products with respect to reduced frequency of administration, potential to achieve high trough levels, and the potential for improved adherence.
  • Illustrate situations (e.g., development of inhibitors, acute bleeds, development of a chronic illness, such as cardiovascular disease) that would require a change in therapy.
     

Faculty

Sheh-Li Chen, Pharm.D., BCOP, CPP
Benign Hematology Clinical Pharmacist Practitioner
University of North Carolina Medical Center
Assistant Professor of Clinical Education
University of North Carolina Eshelmann School of Pharmacy
Chapel Hill, North Carolina

Target Audience

This activity was planned to meet the educational needs of pharmacists who care for patients with hemophilia.

Format

This online activity consists of slide presentations, active learning, an assessment, and evaluation. View the system requirements.

Disclosures

In accordance with ACCME and ACPE Standards for Commercial Support, ASHP policy requires that all faculty, planners, reviewers, staff, and others in a position to control the content of this presentation disclose their financial relationships.

In this activity, no persons associated with this activity have disclosed any relevant financial relationships.

Claim CE Within 60 Days

Participants should claim CE credit for this home-study activity only if they have not claimed credit for the live activity.

To receive CE credit, complete the steps below within 60 days of completing the activity.

  1. View entire presentation and answer all polling questions.
  2. Click "Complete Activity" on the last slide to link to complete the assessment and evaluation.
  3. Verify credits were successfully transferred to CPE Monitor before the ACPE 60-day deadline by checking your NABP eProfile account.

After the 60-day deadline, ASHP will no longer be able to report credit(s).

CPE Information

The American Society of Health-System Pharmacists is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.

ACPE #: 0204-000-19-408-H01-P
Release Date: Monday, September 9, 2019
Expiration Date: Wednesday, September 9, 2020
Activity Type: Application-based
CE Credits: 1.0 hour
Activity Fee: Free of charge