Midyear Symposium & Live Webcast

Monday, December 3, 2012   •   11:30 a.m. – 1:30 p.m. PST
Mandalay Bay Hotel   •   Islander I, Lower Level, North Convention Center
Las Vegas, Nevada

Activity Overview

As the armamentarium of oral agents for prevention and treatment of thrombosis expands, practitioners must develop strategies to deal with the proper management of anticoagulant-related bleeding complications. Patients on oral anticoagulants who are at high risk of bleeding, are actively bleeding, or require emergency invasive procedures will need adjunct therapies that reverse or remove anticoagulant effects sooner than withholding the drug.

This activity will provide an overview of the challenges associated with oral anticoagulant therapies, including risks for developing bleeding complications. Therapeutic options for reversing the effects of oral anticoagulants will be described, focusing on new and emerging options for reversal. Using different patient scenarios, the faculty will explore practical issues in developing a reversal strategy for oral anticoagulant therapy.

Learning Objectives

After attending this application-based educational activity, participants should be able to

  • Identify risk factors for bleeding complications with oral anticoagulant agents.
  • Apply strategies for minimizing the risk of bleeding with oral anticoagulant agents.
  • Describe the relative benefits and limitations of emergent anticoagulant reversal strategies. 
  • Discuss the clinical evidence supporting the use of emergent anticoagulant reversal strategies. 
  • Explain patient-specific treatment options for reversing the effects of oral anticoagulants using laboratory observations.
  • Develop an approach to managing major bleeding in a patient on oral anticoagulation therapy.

Activity Agenda

11:30 am – 11:40 am Welcome and Introductions
Edith A. Nutescu, Pharm.D., FCCP
11:40 am – 12:00 pm Oral Anticoagulant Therapies: A Balancing Act
Edith A. Nutescu, Pharm.D., FCCP
12:00 pm – 12:40 pm Options for Reversing the Effects of Oral Anticoagulants
James S. Kalus, Pharm.D., BCPS (AQ-Cardiology)
12:40 pm – 1:10 pm Practical Issues in Developing an Oral Anticoagulant Reversal Strategy
William E. Dager, Pharm.D., BCPS (AQ-Cardiology)
1:10 pm – 1:30 pm Faculty Discussion and Audience Questions
All Faculty

A box lunch will be provided.

Continuing Education Information

ACPE

The American Society of Health-System Pharmacists is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. This activity provides 2 hours (0.2 CEUs) of continuing pharmacy education credit (ACPE activity #0204-0000-12-438-LO1-P).

Attendees must complete a Continuing Pharmacy Education Request online and may immediately print their official statements of continuing pharmacy education credit at the ASHP CE Center at http://ce.ashp.org following the activity.

Target Audience

This continuing pharmacy education activity was planned to meet the needs of pharmacists in a variety of practice settings, and it would be particularly beneficial for pharmacists, clinical specialists, pharmacy managers, leaders, and educators who are interested in emerging anticoagulant therapies, thrombosis, hematology, cardiology, and patient safety.

Onsite Information

There is no registration for this Midday Symposium. Seating at this activity is on a first-come, first-served basis. Please plan to arrive early. There is no fee to attend this continuing education activity.

Arrangements for Special Assistance

If you have any disability for which you may require an auxiliary aid or special service while participating in this activity, please contact support@ashpadvantage.com.

Faculty

Edith A. NutescuEdith A. Nutescu, Pharm.D., FCCP, Chair and Moderator

Clinical Professor
The University of Illinois at Chicago College of Pharmacy
Director, Antithrombosis Center
The University of Illinois Hospital and Health Sciences System
Chicago, Illinois

Edith A. Nutescu, Pharm.D., FCCP, is Clinical Professor in the Department of Pharmacy Practice, Department of Pharmacy Administration, and Center for Pharmacoeconomic Research at University of Illinois at Chicago College of Pharmacy. She also is Director of the Antithrombosis Center at the University of Illinois at Chicago Medical Center.

Dr. Nutescu earned her Doctor of Pharmacy degree with high honors at the University of Illinois at Chicago College of Pharmacy. After graduation, she went on to complete a pharmacy practice residency at Lutheran General Hospital–Advocate Health Care in Park Ridge, Illinois, and a primary care specialty residency at the University of Illinois at Chicago Medical Center, both accredited by the American Society of Health-System Pharmacists (ASHP).

Dr. Nutescu maintains an active clinical practice and research program. Her research and practice interests are in the areas of comparative effectiveness, health services, and outcomes, with emphasis in cardiovascular diseases, stroke, thrombosis, and antithrombotic therapies. She has authored over 100 scientific articles and book chapters, and she coauthored “Anticoagulation Therapy: A Point-of-care Guide” published by ASHP in 2011. Her research has been funded by the Department of Health and Human Services, Agency for Healthcare Research and Quality, and National Center for Research Resources. She is a recipient of the Ruth L. Kirchstein National Research Service Award for 2010-2012. She has lectured extensively both nationally and internationally on topics related to thrombosis, antithrombotic therapies, cardiovascular diseases, and stroke.

Dr. Nutescu serves on the editorial boards for Pharmacotherapy, Annals of Pharmacotherapy, and Thrombosis, and she previously was on the editorial board for the American Journal of Health-System Pharmacy.  Dr. Nutescu is active in several professional organizations, and she currently is a member of the Board of Regents for the American College of Clinical Pharmacy (ACCP), Board of Directors for Pharmacotherapy, and Board of Directors of the Anticoagulation Forum. She has served on the Oral Anticoagulant National Advisory Board of the National Consumers League Senior Outpatient Medication Safety Coalition and was the only pharmacist member nominated to serve on the steering committee of the National Quality Forum and The Joint Commission that developed “National Consensus Standards for the Prevention and Care of Venous Thrombosis.” Dr. Nutescu has been recognized as a fellow of ACCP and is the recipient of the ACCP 2009 Clinical Practice Award and ASHP Section of Home and Ambulatory Care Practitioners 2010 Distinguished Service Award.

William E. DagerWilliam E. Dager, Pharm.D., BCPS (AQ-Cardiology)

Pharmacist Specialist
UC Davis Medical Center
Sacramento, California

William E. Dager, Pharm.D., BCPS (AQ-Cardiology), is a pharmacist specialist at UC Davis Medical Center in Sacramento, California, where he is responsible for managing challenging cases in anticoagulation, pharmacokinetics, and critical care. He also is clinically active with the cardiology service and serves as the director of the postgraduate year two (PGY-2) residency in cardiology at UC Davis. In addition, Dr. Dager holds three academic positions. He is Clinical Professor of Pharmacy at the University of California, San Francisco (UCSF) School of Pharmacy and Clinical Professor of Medicine at the University of California, Davis (UC Davis) School of Medicine. He also serves as Clinical Professor at the Touro School of Pharmacy in Vallejo, California.

Dr. Dager earned his Doctor of Pharmacy degree at UCSF and completed a residency at the UC Davis Medical Center in Sacramento. In addition, he completed the University of Pittsburgh Nephrology Pharmaceutical Care Preceptorship. He is a board-certified pharmacotherapy specialist and fellow of the American College of Clinical Pharmacy (ACCP), American Society of Health-System Pharmacists (ASHP), California Society of Hospital Pharmacists, and Society of Critical Care Medicine (SCCM).

Dr. Dager's research interests focus on anticoagulation, critical care medicine, cardiovascular disease, and pharmacokinetics and pharmacodynamics. He has authored numerous articles, book chapters, and scientific reviews, and he coauthored “Anticoagulation Therapy: A Point-of-care Guide” published by ASHP in 2011. He also regularly makes presentations at national and international educational conferences. Dr. Dager serves as a reviewer and editorial board member for several medical journals, and he currently is chair of the Editorial Advisory Board Panel on Anticoagulation for The Annals of Pharmacotherapy. He has served as a site coordinator for the ASHP Research and Education Foundation Antithrombotic Pharmacotherapy Traineeship. Dr. Dager has received multiple teaching and professional awards, including the 2008 ACCP Best Practice Award.

James S. KalusJames S. Kalus, Pharm.D., BCPS (AQ-Cardiology)

Senior Manager, Patient Care Services
Department of Pharmacy Services
Henry Ford Hospital
Detroit, Michigan

James S. Kalus, Pharm.D., BCPS (AQ-Cardiology), is Senior Manager of Patient Care Services in the Department of Pharmacy Services at Henry Ford Hospital in Detroit, Michigan. In this position, Dr. Kalus is responsible for planning, implementing, and managing all pharmacy services related to patient care. He also is responsible for formulary management, evaluation, and control. In addition, he oversees staff training and development, as well as pharmacy research. He is Program Director for the postgraduate year one (PGY-1) residency at Henry Ford Hospital and precepts a general inpatient cardiology rotation for pharmacy students and residents.

Dr. Kalus earned both his Bachelor of Science in Pharmacy and Doctor of Pharmacy degrees at the University of Toledo in Toledo, Ohio. After completing a residency at the Medical University of South Carolina in Charleston, he did a two-year cardiovascular research fellowship through Hartford Hospital and the University of Connecticut in Hartford, Connecticut. Dr. Kalus was honored with the Outstanding Young Alumnus Award from the University of Toledo in 2009.

Before assuming his current position, Dr. Kalus served as Assistant Professor at the Eugene Applebaum College of Pharmacy and Health Sciences at Wayne State University in Detroit, Michigan. He is board certified as a pharmacotherapy specialist with added qualifications in cardiology.

In his research, Dr. Kalus focuses on cardiovascular disease, including the pathophysiology of atrial fibrillation (AF) occurring after cardiac surgery, novel strategies for the treatment and prevention of AF, and practice-based research related to anticoagulation. He has authored several textbook chapters and many articles published in peer-reviewed journals, including the American Journal of Health-System Pharmacy, Annals of Pharmacotherapy, Annals of Thoracic Surgery, Circulation, Journal of Electrocardiology, Journal of Hospital Medicine, Pharmacoeconomics, and Pharmacotherapy. He also serves on the editorial board of The Annals of Pharmacotherapy, Cardiology Panel.

Complementing the practice and research interests of Dr. Kalus is his involvement in professional associations. An active member of the American Society of Health-System Pharmacists (ASHP), he regularly speaks at educational sessions at the ASHP Midyear Clinical Meeting. As a member of the 2007 Research Affairs Committee of the American College of Clinical Pharmacy, he co-authored the report, “Recommended Education for Pharmacists as Competitive Clinical Scientists,” published in March 2009. The Southeastern Michigan Society of Health-System Pharmacists honored him with the 2008 Preceptor of the Year award and the 2006 Innovative Practice Award. He also has received the Drug Therapy Research Award from the ASHP Research and Education Foundation, and, in 2009, Dr. Kalus and his colleagues were finalists for the Foundation's Excellence in Medication Use Safety Award.

Webcast Information and Registration

This symposium will be broadcast live from Las Vegas, Nevada, as a webcast so that pharmacists unable to attend this year’s ASHP Midyear Clinical Meeting can participate.

Register for Webcast

After registration, you will receive an e-mail confirmation with instructions for joining the webcast.

Download Handout

Frequently Asked Questions for Webcasts

What is a live webcast? A live webcast brings the presentation to you – at your work place or in your home. You view and hear the presentations in “real time” complete with slides and video of the speakers and have the opportunity to ask questions at the end of the activity. Continuing pharmacy education (CPE) credits earned through participation in webcasts qualify as live CPE credit.  Please join the webcast at least 5 minutes before the scheduled start time for important activity announcements.

How do I register? Click the Register for Webcast button. You will be emailed a confirmation with webcast connection information.

How do I process my CPE? After completion of this webcast, you will process your CPE online and print your statement of credit at http://ce.ashp.org. You will need the Activity and Session Codes that will be announced at the end of the webcast. Complete CPE processing instructions will be included in your handout. If you have questions about processing CPE online, contact support@ashpadvantage.com.

What if I would like to arrange for my colleagues to participate in this webcast as a group? One person should register for the webcast and will receive the webcast linking instructions via email. Each participant processes his or her CPE statement online at the conclusion of the activity.

How do I ask a question of the presenters during the webcast?
Click the “Ask a Question” bubble iconChat Icon to type a question and your email. The speakers will answer as many questions as possible at the conclusion of the activity. Responses to technical questions will be sent to the email address you provided.

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Mac®

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* If Silverlight is not detected on your computer when viewing a presentation, you will be automatically prompted to install the plug-in. Silverlight only needs to be installed once and will then be available for watching any other presentations.

Classic Player Option
If you are unable to install Silverlight or your bandwidth speed is slower than required, another version of the webcast is available.  The requirements are as follows:

Microsoft® Windows®

Mac®

Linux

  • Microsoft® Windows 7, Windows Vista, Windows XP, Windows Server 2008
  • Windows Server 2003
  • Internet Explorer 6.0 SP1 or later, Firefox® 2.0 or later, or Google™ Chrome 1.0
  • Windows Media® Player 9.0 or later
  • Broadband Internet connection (256Kbps or more)
  • Mac OS X 10.4.8 or later
  • Safari™ 2.0.4 or later or Firefox 2.0 or later
  • Microsoft Silverlight 1.0 or later*
  • Broadband Internet connection (256Kbps or more)
  • SUSE Linux Enterprise Desktop 10, openSUSE 11.0 or later, Ubuntu 8.04, or Fedora Core 9
  • Firefox 2.0 or 3.0 depending on Linux operating system
  • Moonlight™ 1.0
  • Microsoft Media Pack for Moonlight
  • Broadband Internet connection (256Kbps or more)

* If Silverlight is not detected on your computer when viewing a presentation, you will be automatically prompted to install the plug-in. Silverlight only needs to be installed once and will then be available for watching any other presentations.

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iPhone and iPod

Android

BlackBerry

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  • Android 4.0 or later
  • On-demand playback only
  • Wi-Fi or cellular data connection (3G or higher)
  • BlackBerry OS 7.0 or later
  • On-demand playback only
  • Wi-Fi or cellular data connection (3G or higher)