Ask the Experts: Developing a Systems Approach for Managing Reversal of Oral Anticoagulant Therapy

Webinar Information and Registration

Wednesday, March 20, 2013   •   1-2 pm EDT

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For Pharmacists
ACPEThe American Society of Health-System Pharmacists is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. This activity provides 1 hour (0.1 CEU) of continuing pharmacy education credit (activity # 0204-0000-13-400-L01-P).

Methods and Format

This is a live web-based activity consisting of audio, presentation slides, and an activity evaluation tool.  Participants must participate in the entire presentation and complete the course evaluation to receive continuing pharmacy education credit. Participants may print their official statements of continuing pharmacy education credit immediately following the activity.  This activity is provided free of charge.
Click here for full CE processing instructions.

Target Audience

This continuing pharmacy education activity was planned to meet the needs of pharmacists in a variety of practice settings, and it would be particularly beneficial for pharmacists, clinical specialists, pharmacy managers, leaders, and educators who are interested in oral anticoagulant therapies, thrombosis, hematology, cardiology, and patient safety.

Webinar Overview

This activity will provide health-system pharmacists with a foundation for developing a systems approach for reversing oral anticoagulant therapy given the paucity of data available. The faculty will also offer clinical pearls related to the dosing and timing of agents used to reverse oral anticoagulant therapy.

The content for this live webinar is based on questions raised by participants in a recent educational symposium on this topic. Time for questions and answers from the webinar audience will be provided at the end of the presentation.

Learning Objectives

At the conclusion of this application-based educational activity, participants should be able to

  • Outline elements of a systems approach to managing reversal of oral anticoagulant therapy.
  • Apply practical considerations in the dosing and timing of agents used to reverse oral anticoagulant therapy.


Edith A. NutescuEdith A. Nutescu, Pharm.D., FCCP, Chair and Moderator

Clinical Professor
The University of Illinois at Chicago College of Pharmacy
Director, Antithrombosis Center
The University of Illinois Hospital and Health Sciences System
Chicago, Illinois

Edith A. Nutescu, Pharm.D., FCCP, is Clinical Professor in the Department of Pharmacy Practice, Department of Pharmacy Administration, and Center for Pharmacoeconomic Research at University of Illinois at Chicago College of Pharmacy. She also is Director of the Antithrombosis Center at the University of Illinois at Chicago Medical Center.

Dr. Nutescu earned her Doctor of Pharmacy degree with high honors at the University of Illinois at Chicago College of Pharmacy. After graduation, she went on to complete a pharmacy practice residency at Lutheran General Hospital–Advocate Health Care in Park Ridge, Illinois, and a primary care specialty residency at the University of Illinois at Chicago Medical Center, both accredited by the American Society of Health-System Pharmacists (ASHP).

Dr. Nutescu maintains an active clinical practice and research program. Her research and practice interests are in the areas of comparative effectiveness, health services, and outcomes, with emphasis in cardiovascular diseases, stroke, thrombosis, and antithrombotic therapies. She has authored over 100 scientific articles and book chapters, and she coauthored “Anticoagulation Therapy: A Point-of-care Guide” published by ASHP in 2011. Her research has been funded by the Department of Health and Human Services, Agency for Healthcare Research and Quality, and National Center for Research Resources. She is a recipient of the Ruth L. Kirchstein National Research Service Award for 2010-2012. She has lectured extensively both nationally and internationally on topics related to thrombosis, antithrombotic therapies, cardiovascular diseases, and stroke.

Dr. Nutescu serves on the editorial boards for Pharmacotherapy, Annals of Pharmacotherapy, and Thrombosis, and she previously was on the editorial board for the American Journal of Health-System Pharmacy.  Dr. Nutescu is active in several professional organizations, and she currently is a member of the Board of Regents for the American College of Clinical Pharmacy (ACCP), Board of Directors for Pharmacotherapy, and Board of Directors of the Anticoagulation Forum. She has served on the Oral Anticoagulant National Advisory Board of the National Consumers League Senior Outpatient Medication Safety Coalition and was the only pharmacist member nominated to serve on the steering committee of the National Quality Forum and The Joint Commission that developed “National Consensus Standards for the Prevention and Care of Venous Thrombosis.” Dr. Nutescu has been recognized as a fellow of ACCP and is the recipient of the ACCP 2009 Clinical Practice Award and ASHP Section of Home and Ambulatory Care Practitioners 2010 Distinguished Service Award.

William E. DagerWilliam E. Dager, Pharm.D., BCPS (AQ-Cardiology)

Pharmacist Specialist
UC Davis Medical Center
Sacramento, California

William E. Dager, Pharm.D., BCPS (AQ-Cardiology), is a pharmacist specialist at UC Davis Medical Center in Sacramento, California, where he is responsible for managing challenging cases in anticoagulation, pharmacokinetics, and critical care. He also is clinically active with the cardiology service and serves as the director of the postgraduate year two (PGY-2) residency in cardiology at UC Davis. In addition, Dr. Dager holds three academic positions. He is Clinical Professor of Pharmacy at the University of California, San Francisco (UCSF) School of Pharmacy and Clinical Professor of Medicine at the University of California, Davis (UC Davis) School of Medicine. He also serves as Clinical Professor at the Touro School of Pharmacy in Vallejo, California.

Dr. Dager earned his Doctor of Pharmacy degree at UCSF and completed a residency at the UC Davis Medical Center in Sacramento. In addition, he completed the University of Pittsburgh Nephrology Pharmaceutical Care Preceptorship. He is a board-certified pharmacotherapy specialist and fellow of the American College of Clinical Pharmacy (ACCP), American Society of Health-System Pharmacists (ASHP), California Society of Hospital Pharmacists, and Society of Critical Care Medicine (SCCM).

Dr. Dager's research interests focus on anticoagulation, critical care medicine, cardiovascular disease, and pharmacokinetics and pharmacodynamics. He has authored numerous articles, book chapters, and scientific reviews, and he coauthored “Anticoagulation Therapy: A Point-of-care Guide” published by ASHP in 2011. He also regularly makes presentations at national and international educational conferences. Dr. Dager serves as a reviewer and editorial board member for several medical journals, and he currently is chair of the Editorial Advisory Board Panel on Anticoagulation for The Annals of Pharmacotherapy. He has served as a site coordinator for the ASHP Research and Education Foundation Antithrombotic Pharmacotherapy Traineeship. Dr. Dager has received multiple teaching and professional awards, including the 2008 ACCP Best Practice Award.

Frequently Asked Questions for Webinars

What is a live webinar?
A live webinar brings the presentation to you – at your work place, in your home, through a staff in-service program.  You listen to the speaker presentation in “real time” as you watch the slides on the screen.  You will have the opportunity to ask the speaker questions at the end of the program.  Please join the conference at least 5 minutes before the scheduled start time for important announcements.

How do I process my Continuing Education (CE) credit?
Continuing pharmacy education for this activity will be processed on ASHP’s new eLearning system and reported directly to CPE Monitor.  After completion of the live webinar, you will process your CPE and print your statement of credit online at To process your CPE, you will need the enrollment code that will be announced at the end of the webinar.

View full CE processing instructions (PDF).

What if I would like to arrange for my colleagues to participate in this webinar as a group?
One person serving as the group coordinator should register for the webinar.  That group coordinator will receive an e-mail confirmation with instructions for joining the webinar.  A few minutes before the webinar begins, the group coordinator should launch the webinar link. Once the webinar has been activated, the coordinator will have the option to open the audio via VoIP (Voice Over IP) on the webinar toolbar or use a touch tone phone with the provided dial-in information.  At the conclusion of the activity, the group coordinator will complete a brief online evaluation and report the number of participants at that site.  Each participant will process his or her individual continuing education statement online.

What do I need in order to participate in the webinar?

  • Computer with internet access and basic system requirements. When you register, the webinar system will assess your system to ensure compatibility.
  • Telephone to dial the toll-free number and listen to the presentation (if you choose not to use VoIP via your computer).

Webinar System Requirements
Be sure to view the webinar system requirements for Windows, Mac, iOS, and Android prior to the activity.